Twice a day, about 3 hours for each time(Do not use while sleeping)
After 20 minutes you could feel the heat(If you do not feel the heat, you can just wipe the surface of the insoles with wet towel).
It is normal that some people with sensitive skin may feel burn or skin turns red. If it hurts your skin, you could shorten use time according to individual circumstance.
You could also wear the brace through clothing but the heating effect will decrease and the magnetic effect will work as normal.
Apply on knee directly.